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ea0032oc5.2 | Reproduction | ECE2013

The (TAAAA)n polymorphism in the SHBG gene is related to prenatal androgenization of female fetus: possible implications of the developmental origin of metabolic disorders

Pamporaki Christina , Xita Nectaria , Lazaros Leandros , Makridimas George , Georgiou Ioannis , kolios George , Plachouras Nikolaos , Tsatsoulis Agathocles

Introduction: The aim of this study was to examine whether the distribution of SHBG (TAAAA)n repeat variants contributes to the exposure of the female fetus to androgen excess, by influencing the, in utero, androgen availability.Methods: The study population consisted of 100 pregnant women that carried female fetuses and underwent the procedure of amniocentesis due to age (older than 35). Blood samples and amniotic fluid samples were dr...

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Endocrine Abstracts

The (TAAAA)n polymorphism in the SHBG gene is related to prenatal androgenization of female fetus: possible implications of the developmental origin of metabolic disorders

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